PROBING THE MECHANICAL DYNAMICS OF SUBCELLULAR ORGANELLES
Keywords:
Subcellular organelles, mechanical dynamics, cellular biomechanicsAbstract
This study investigates the mechanical dynamics of subcellular organelles, shedding light on their structural integrity, deformability, and response to mechanical forces. Subcellular organelles play crucial roles in various cellular functions, and understanding their mechanical behavior is essential for elucidating cellular biomechanics and pathophysiological processes. Through a combination of experimental techniques, including atomic force microscopy, optical tweezers, and micropipette aspiration, this research probes the mechanical properties of subcellular organelles at the nanoscale. Key findings reveal the diverse mechanical characteristics of organelles such as the nucleus, mitochondria, endoplasmic reticulum, and lysosomes, and their implications for cellular function and health. Insights from this study contribute to advancing our understanding of cellular mechanics and hold potential for developing novel therapeutic strategies targeting mechanobiology-related diseases.
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