CLINICAL AND PATHOPHYSIOLOGICAL ASPECTS OF VIRAL HEPATITI

Authors

  • Dr. Razial Kamal Independent researcher of medical centre in Bangladesh

Keywords:

viral hepatitis, hepatitis B, hepatitis C, hepatocellular carcinoma, antiviral therapy

Abstract

Viral hepatitis represents a major global health burden, affecting millions of people worldwide and causing significant morbidity and mortality. The disease is primarily caused by hepatotropic viruses (hepatitis A, B, C, D, and E), each with distinct transmission routes, clinical manifestations, and long-term outcomes. Chronic viral hepatitis, particularly types B and C, is strongly associated with cirrhosis and hepatocellular carcinoma, making it a critical focus for prevention and treatment. This article reviews the pathophysiological mechanisms, clinical features, and pharmacological management of viral hepatitis, highlighting current challenges and advances in antiviral therapy.

Downloads

Download data is not yet available.

References

World Health Organization. (2022). Global progress report on HIV, viral hepatitis and sexually transmitted infections. WHO Press.

Terrault, N. A., Lok, A. S., McMahon, B. J., Chang, K. M., Hwang, J. P., et al. (2018). Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 guidance. Hepatology, 67(4), 1560–1599.

Pawlotsky, J. M. (2016). Hepatitis C virus resistance to direct-acting antiviral drugs in interferon-free regimens. Gastroenterology, 151(1), 70–86.

Ringehan, M., McKeating, J. A., & Protzer, U. (2017). Viral hepatitis and liver cancer. Philosophical Transactions of the Royal Society B: Biological Sciences, 372(1732), 20160274.

Polaris Observatory Collaborators. (2022). Global prevalence and genotype distribution of hepatitis C virus infection. The Lancet Gastroenterology & Hepatology, 7(8), 724–735.

Downloads

Published

2025-10-02

How to Cite

Dr. Razial Kamal. (2025). CLINICAL AND PATHOPHYSIOLOGICAL ASPECTS OF VIRAL HEPATITI. Journal of Applied Science and Social Science, 15(09), 1048–1050. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/1941

Issue

Vol. 15 No. 09 (2025): Volume 15 Issue 09

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

All content published in the Journal of Applied Science and Social Science (JASSS) is protected by copyright. Authors retain the copyright to their work, and grant JASSS the right to publish the work under a Creative Commons Attribution License (CC BY). This license allows others to distribute, remix, adapt, and build upon the work, even commercially, as long as they credit the author(s) for the original creation.