SYSTEMIC INFLAMMATION, HEMOSTSIS AND SPECTR OF LIPID IN PATIENTS WITH BRONCHIAL ASTHMA
Keywords:
systemic inflammation, cytokine, coagulation, plasminogen.Abstract
Currently, considerable attention is devoted to identifying risk factors for the development of Bronchial asthma (BA). Inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α) and various interleukins (ILs), play a key role in the emergence of hemostatic disorders, particularly in children aged 6 to 8 years. Interleukin-6 (IL-6) serves as the primary cytokine initiating coagulation, while TNF-α also affects coagulation indirectly. Interleukin-8 (IL-8) participates in the regulation of blood coagulation by influencing the secretion of procoagulant and anticoagulant factors, as well as plasminogen inhibitors
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