THE EFFECT OF HYDROXYTYROSOL ON THE CARDIOVASCULAR SYSTEM: ITS ROLE IN LIPID PROFILE REGULATION, ENDOTHELIAL FUNCTION, AND INHIBITION OF ATHEROSCLEROSIS

Authors

  • Khakimov Muhammadi Khamidjon ugli Department of Biological Chemistry, Andijan State Medical Institute, Uzbekistan, Andijan

Keywords:

Hydroxytyrosol; polyphenols; cardiovascular system; lipid profile; LDL oxidation; HDL; endothelial function; oxidative stress; atherosclerosis; NF-κB; eNOS; antioxidant; cardioprotective; anti-inflammatory activity.

Abstract

This article analyzes the effects of hydroxytyrosol (3,4-dihydroxyphenyl ethanol) on the cardiovascular system, focusing on its role in modulating lipid profile, endothelial function, and the progression of atherosclerosis based on modern scientific sources and experimental findings. The study highlights the molecular mechanisms through which hydroxytyrosol restores cardiovascular homeostasis via its antioxidant, anti-inflammatory, anti-atherogenic, and antithrombotic properties. The results indicate that HT reduces LDL oxidation, enhances functional activity of HDL, increases endothelial NO synthesis, decreases the expression of inflammatory mediators, and improves atherosclerotic plaque stability. The obtained data provide a scientific basis for the use of hydroxytyrosol as a cardioprotective nutraceutical.

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References

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Published

2025-11-19

How to Cite

Khakimov Muhammadi Khamidjon ugli. (2025). THE EFFECT OF HYDROXYTYROSOL ON THE CARDIOVASCULAR SYSTEM: ITS ROLE IN LIPID PROFILE REGULATION, ENDOTHELIAL FUNCTION, AND INHIBITION OF ATHEROSCLEROSIS. Journal of Applied Science and Social Science, 15(11), 448–452. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/2411

Issue

Vol. 15 No. 11 (2025): Volume 15 Issue 11

Section

Articles

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