VENOUS ENCEPHALOPATHY: EARLY DIAGNOSIS (literature review)
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xAbstract
Venous encephalopathy (including acute cerebral sinus thrombosis syndrome, chronic forms of venous insufficiency, and venous collagenoses) is a significant cause of neurological impairment, potentially leading to parenchymal changes, cerebral edema, and hemorrhagic complications. Early diagnosis determines the outcome and enables timely initiation of anticoagulant or interventional therapy. This article discusses the pathophysiology, clinical presentation, laboratory and instrumental markers, and a practical diagnostic algorithm, focusing on the role of MRI/MRV, CT/CTV, SWI, and laboratory tests (D- dimer and thrombotic panels). Risk assessment schemes, an algorithm for action in emergency and elective situations, and recommendations for monitoring and selection of additional tests are proposed.
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References
StatPearls : Cerebral Venous Sinus Thrombosis . (Review, available through the NCBI Bookshelf ). ( NCBI )
Lahna D. et al., Venous Collagenosis as Pathogenesis of White Matter Lesions (Ann Neurol, 2022) - role venous collagenoses in WML. ( PMC )
Mittal S. et al., Susceptibility-weighted imaging: technical aspects and clinical applications (AJNR, 2009) - use of SWI in venous pathologies . ( ajnr.org )
Heldner MR. et al., Prediction of cerebral venous thrombosis with D-dimer (neurology / research 2020) - data By diagnostic characteristics of D- dimer in CVT. ( neurology.org )
Li A.Y. et al., A Case-Based Review of Cerebral Venous Infarcts With Imaging Correlates (Front Radiology, 2021) - practical radiological perspective . ( Frontiers )
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