EXPLAINING THE TOPIC OF HAND AND FOOT BONES TO STUDENTS IN AN EASY WAY
Keywords:
Shoulder, upper limb, hand bones.Abstract
The limb bud first appears in the proximal fetus around the fifth week of development. From this point, various HOX genes govern the growth of the limb. The stylopod, zeugopod, and autopod are the three growth zones of the limb bud corresponding to the humerus, ulna and radius, and hand, respectively. Ectoderm differentiates into the apical ectodermal ridge, non-ridge ectoderm, and zone of polarizing activity. These zones carry essential roles in differentiation. For example, the removal of the apical ectodermal ridge early in limb development will result in the presence of only stylopod development. Removal of the apical ectodermal ridge later in development will result in the formation of the stylopod and zeugopod but no autopod, leading to the fetus not developing a hand.
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