SIPROFLOKS-AK 250 AS A POTENTIAL MEDICINE FOR THE TREATMENT OF DIARRHEA

Authors

  • Turg’unov Dilshod MSc Pharmaceutical Sciences, lecturer Department of Pharmaceutical Sciences of Kokand University Andijan Branch
  • V.R. Khaydarov Professor of the Department of Industrial Technology of Medicines of the Tashkent Pharmaceutical Institute

Keywords:

SIPROFLOKS-AK 250, ciprofloxacin, diarrhea, antibacterial therapy, fluoroquinolones

Abstract

 Diarrheal diseases remain a major global health problem, particularly in developing countries, where bacterial infections are a leading cause. Fluoroquinolone antibiotics, including ciprofloxacin-based formulations, are widely used for the management of infectious diarrhea. SIPROFLOKS-AK 250 is a ciprofloxacin-containing pharmaceutical product with broad-spectrum antibacterial activity. This article evaluates the potential role of SIPROFLOKS-AK 250 in the treatment of diarrhea caused by bacterial pathogens. The study reviews its pharmacological properties, antibacterial spectrum, clinical applicability, and safety considerations. Based on available data, SIPROFLOKS-AK 250 demonstrates significant potential as an effective therapeutic option for bacterial diarrhea when used appropriately.

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References

ICH Q2(R1) — Validation of Analytical Procedures: Text and Methodology. International Conference on Harmonisation. (Accessed via ICH database). (ICH Database)

Scherer R, et al. Determination of Ciprofloxacin in Pharmaceutical Formulations by RP-HPLC. J Chromatogr A / related publication (example method using XBridge C18, detection at 278 nm). PMC article. (PMC)

Ali SA, et al. An RP-HPLC method for the determination of Ciprofloxacin HCl. (method development and validation; detection at 278 nm, buffer/ACN mobile phases). Journal / report (2011). (JAPS)

Vaghela BK, et al. A novel validated stability-indicating HPLC method for quantitative determination of ciprofloxacin and tinidazole impurities. Journal / PMC (2013). (PMC)

Shohag MH, et al. Post-market quality assessment of 22 ciprofloxacin brands using validated RP-HPLC. ScienceDirect (2023). (sciencedirect.com)

Goyal A., Anju et al. A Validated RP-HPLC Method for Estimation of Ciprofloxacin and Tinidazole in Combined Tablet Dosage Form. International Journal of Pharmaceutical Chemistry and Analysis (2015). (SciSpace)

Yuqori samarali suyuqlik xromatografiyasi (HPLC) yordamida dekserich suyuq ekstraktidagi rutin kontsentratsiyasini tahlil qilish

M Axmatoxunova, A Shokirov - Journal of Integrated Education and Research, 2024

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Published

2025-12-19

How to Cite

Turg’unov Dilshod, & V.R. Khaydarov. (2025). SIPROFLOKS-AK 250 AS A POTENTIAL MEDICINE FOR THE TREATMENT OF DIARRHEA. Journal of Applied Science and Social Science, 15(12), 911–913. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/2741

Issue

Vol. 15 No. 12 (2025): Volume 15 Issue 12

Section

Articles

License

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