ANATOMICAL CHANGE OF THE UTERUS IN ENDOMETRIOSIS

Authors

  • Tuychieva Shakhnoza Mukhammadjonovna Kokand university Andijan branch Assistant of the Department of Anatomy, Clinical and Pathological Anatomy

Keywords:

endometriosis, adenomyosis, uterine anatomy, junctional zone, fibrosis, neuroangiogenesis, transvaginal ultrasound, MRI, fertility.

Abstract

This IMRAD-structured review addresses uterine anatomical and morphofunctional changes in endometriosis. We synthesize evidence on fibrotic–inflammatory remodeling of the myometrium and the junctional zone, coexistent adenomyosis, alterations in uterine position and mobility, neuroangiogenesis, and imaging features on transvaginal ultrasonography and MRI, alongside histopathology and laparoscopic mapping. Disruptions of uterine peristalsis, progesterone resistance, endometrial receptor changes, clinical implications (pain, infertility), and the need for multidisciplinary diagnostic and therapeutic strategies are discussed.

Downloads

Download data is not yet available.

References

Giudice, L. C. Clinical practice. Endometriosis. Boston, MA: Massachusetts Medical Society, New England Journal of Medicine; 2010. 362(25):2389–2398 pages.

Zondervan, K. T.; Becker, C. M.; Missmer, S. A. Endometriosis. Boston, MA: Massachusetts Medical Society, New England Journal of Medicine; 2020. 382(13):1244–1256 pages.

Vercellini, P.; Viganò, P.; Somigliana, E.; Fedele, L. Endometriosis: pathogenesis and treatment. London: Nature Publishing Group, Nature Reviews Endocrinology; 2014. 10(5):261–275 pages.

Chapron, C.; Fauconnier, A.; Vieira, M.; Barakat, H.; Dousset, B.; Pansini, V.; Vacher-Lavenu, M.-C.; Dubuisson, J.-B. Deep infiltrating endometriosis: pathogenetic implications of the anatomical distribution. Oxford, UK: Oxford University Press, Human Reproduction; 2006. 21(7):1839–1845 pages.

Burney, R. O.; Giudice, L. C. Pathogenesis and pathophysiology of endometriosis. Amsterdam: Elsevier, Fertility and Sterility; 2012. 98(3):511–519 pages.

Bazot, M.; Daraï, E. Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of deep endometriosis. Amsterdam: Elsevier, Fertility and Sterility; 2007. 88(5):1183–1187 pages.

Bulun, S. E. Endometriosis. Boston, MA: Massachusetts Medical Society, New England Journal of Medicine; 2009. 360(3):268–279 pages.

Sampson, J. A. Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity. St. Louis, MO: C. V. Mosby Company, American Journal of Obstetrics and Gynecology; 1927. 14(4):422–469 pages.

Dunselman, G. A. J.; Vermeulen, N.; Becker, C.; Calhaz-Jorge, C.; D’Hooghe, T.; et al. ESHRE guideline: management of women with endometriosis. Oxford, UK: Oxford University Press, Human Reproduction; 2014. 29(3):400–412 pages.

Downloads

Published

2025-12-20

How to Cite

Tuychieva Shakhnoza Mukhammadjonovna. (2025). ANATOMICAL CHANGE OF THE UTERUS IN ENDOMETRIOSIS. Journal of Applied Science and Social Science, 15(12), 933–937. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/2744

Issue

Vol. 15 No. 12 (2025): Volume 15 Issue 12

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

All content published in the Journal of Applied Science and Social Science (JASSS) is protected by copyright. Authors retain the copyright to their work, and grant JASSS the right to publish the work under a Creative Commons Attribution License (CC BY). This license allows others to distribute, remix, adapt, and build upon the work, even commercially, as long as they credit the author(s) for the original creation.