IMPACT OF NUTRITIONAL DEFICIENCIES ON IMMUNE SYSTEM DEVELOPMENT IN EARLY CHILDHOOD

Authors

  • Kasimova K.Z. Andijan State Medical Institute, Uzbekistan

Keywords:

Nutritional deficiencies, immune system development, early childhood, micronutrients, pediatric health

Abstract

Adequate nutrition during early childhood is essential for optimal growth, development, and maturation of the immune system. Nutritional deficiencies, particularly of essential vitamins and minerals, can impair immune responses and increase susceptibility to infections. This study examines the impact of nutritional deficiencies on immune system development in early childhood, with a focus on micronutrients such as iron, zinc, vitamin A, vitamin D, and vitamin C. Evidence indicates that insufficient intake of these nutrients adversely affects both innate and adaptive immunity, leading to increased infection rates and delayed immune maturation. Early identification and correction of nutritional deficiencies are critical for supporting immune competence and improving child health outcomes.

 

Downloads

Download data is not yet available.

References

World Health Organization. Guiding principles for complementary feeding of the breastfed child. WHO; 2003.

Calder PC, et al. Nutrition and immunity: Lessons for the future. Nutrients. 2020;12:2854.

Black RE, et al. Maternal and child undernutrition. Lancet. 2013;382:427–451.

Prentice AM. Iron metabolism and immune function. Am J Clin Nutr. 2008;88:1525S–1531S.

Shankar AH, Prasad AS. Zinc and immune function. Am J Clin Nutr. 1998;68:447S–463S.

Stephensen CB. Vitamin A, infection, and immune function. Annu Rev Nutr. 2001;21:167–192.

Martineau AR, et al. Vitamin D and respiratory infections. BMJ. 2017;356:i6583.

Wintergerst ES, et al. Role of micronutrients in immune function. Br J Nutr. 2007;98:S59–S69.

Downloads

Published

2025-12-24

How to Cite

Kasimova K.Z. (2025). IMPACT OF NUTRITIONAL DEFICIENCIES ON IMMUNE SYSTEM DEVELOPMENT IN EARLY CHILDHOOD. Journal of Applied Science and Social Science, 15(12), 1104–1107. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/2787