PHARMACOLOGICAL EVALUATION OF THE HYPOGLYCEMIC ACTIVITY OF THE “ANTIDIABETOL” PHYTOCOMPOSITION IN EXPERIMENTAL MODELS OF DIABETES MELLITUS
Keywords:
type 2 diabetes mellitus, phytotherapy, Antidiabetol, hypoglycemic activity, preclinical study, statistics.Abstract
The study presents statistically substantiated results of a preclinical pharmacological evaluation of the “Antidiabetol” phytocomposition developed from local medicinal plants. Hypoglycemic efficacy was assessed in alimentary and adrenaline-induced hyperglycemia models, along with toxicological safety parameters. The phytocomposition demonstrated a statistically significant reduction in blood glucose levels (p < 0.05–0.01) without cumulative, allergic, embryotoxic, or cardiovascular adverse effects. These findings support the potential clinical relevance of “Antidiabetol” for the management of type 2 diabetes mellitus.
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