PHARMACOLOGICAL EFFICACY OF SINOTAN COLLECTION AGAINST HELMINTHS

Abstract

Helminthic infections remain a major public health concern worldwide, necessitating the continuous search for effective and safe antihelminthic agents. This study evaluates the pharmacological efficacy of the Sinotan collection, a complex of biologically active compounds with potential antihelminthic properties. The research focuses on its effects on helminth viability, neuromuscular activity, and metabolic processes, as well as its general toxicity profile. Experimental investigations demonstrated that the Sinotan collection exhibits strong, dose-dependent antihelminthic activity, leading to reduced motility, paralysis, and death of helminths. Additionally, the Sinotan collection showed low toxicity toward the host organism, highlighting its potential as a promising pharmacological agent for the treatment and prevention of helminthiasis.