CLINICAL FEATURES OF CARDIOVASCULAR ADAPTATION IN CHILDREN AFTER SURGICAL CORRECTION OF TETRALOGY OF FALLOT
Keywords:
Tetralogy of Fallot; cardiovascular adaptation; postoperative period; hemodynamics; right ventricle; arrhythmias; echocardiography.Abstract
Introduction: Tetralogy of Fallot is a common cyanotic congenital heart defect requiring surgical repair. Despite advances in surgical techniques, a portion of patients demonstrates postoperative cardiovascular maladaptation. This study aimed to evaluate the features of cardiovascular adaptation in different postoperative periods.
Materials and Methods: Eighty children after early surgical repair (mean age 7.2 ± 2.0 months) were examined. Hemodynamics, echocardiographic parameters, rhythm disturbances, and exercise tolerance were analyzed across several follow-up stages.
Results: Positive hemodynamic dynamics were observed in 81.3% of patients. In 72%, transient enlargement of right ventricular end-diastolic volume was detected, with functional recovery by one month. Arrhythmias occurred in 15% early and 5% at six months. Exercise tolerance increased by 25% by three months.
Discussion and conclusion: Cardiovascular adaptation proceeds in a stepwise manner and is influenced by myocardial condition, bypass duration, and hypoxic burden. Comprehensive monitoring is essential for optimizing postoperative management and improving long-term outcomes.
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References
Anderson R.H., Penny D.J. Pediatric Cardiology. Springer, 2020.
Kirklin J.W., Barratt-Boyes B.G. Cardiac Surgery. Wiley-Blackwell, 2019.
Marino B.S., et al. Hemodynamic adaptation in congenital heart disease. Pediatric Critical Care Medicine, 2022.
Singh G.K. Tetralogy of Fallot: postoperative physiology. Current Pediatric Reviews, 2023.
Jacobs M.L., et al. Outcomes after early repair of Tetralogy of Fallot. Annals of Thoracic Surgery, 2021.
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