CLINICAL FEATURES OF CARDIOVASCULAR ADAPTATION IN CHILDREN AFTER SURGICAL CORRECTION OF TETRALOGY OF FALLOT

Authors

  • Karimova Khafiza Bakhtiyor kizi, Usmonkulov Murodjon Ilhomjon ugli Samarkand State Medical University, Samarkand, Uzbekistan

Keywords:

Tetralogy of Fallot; cardiovascular adaptation; postoperative period; hemodynamics; right ventricle; arrhythmias; echocardiography.

Abstract

Introduction: Tetralogy of Fallot is a common cyanotic congenital heart defect requiring surgical repair. Despite advances in surgical techniques, a portion of patients demonstrates postoperative cardiovascular maladaptation. This study aimed to evaluate the features of cardiovascular adaptation in different postoperative periods.

Materials and Methods: Eighty children after early surgical repair (mean age 7.2 ± 2.0 months) were examined. Hemodynamics, echocardiographic parameters, rhythm disturbances, and exercise tolerance were analyzed across several follow-up stages.

Results: Positive hemodynamic dynamics were observed in 81.3% of patients. In 72%, transient enlargement of right ventricular end-diastolic volume was detected, with functional recovery by one month. Arrhythmias occurred in 15% early and 5% at six months. Exercise tolerance increased by 25% by three months.

Discussion and conclusion: Cardiovascular adaptation proceeds in a stepwise manner and is influenced by myocardial condition, bypass duration, and hypoxic burden. Comprehensive monitoring is essential for optimizing postoperative management and improving long-term outcomes.

 

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References

Anderson R.H., Penny D.J. Pediatric Cardiology. Springer, 2020.

Kirklin J.W., Barratt-Boyes B.G. Cardiac Surgery. Wiley-Blackwell, 2019.

Marino B.S., et al. Hemodynamic adaptation in congenital heart disease. Pediatric Critical Care Medicine, 2022.

Singh G.K. Tetralogy of Fallot: postoperative physiology. Current Pediatric Reviews, 2023.

Jacobs M.L., et al. Outcomes after early repair of Tetralogy of Fallot. Annals of Thoracic Surgery, 2021.

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Published

2026-01-13

How to Cite

Karimova Khafiza Bakhtiyor kizi, Usmonkulov Murodjon Ilhomjon ugli. (2026). CLINICAL FEATURES OF CARDIOVASCULAR ADAPTATION IN CHILDREN AFTER SURGICAL CORRECTION OF TETRALOGY OF FALLOT. Journal of Applied Science and Social Science, 16(01), 212–217. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/2946