ANTIMICROBIAL RESISTANCE: PHARMACOLOGICAL AND PUBLIC HEALTH CRISIS

Authors

  • Dr. Krishna Badal MBBS, MD Associate Professor, Department of Pediatrics Faculty of International Students, Asia International University

Keywords:

Antimicrobial, Resistance, Pharmacology, Public Health, Crisis

Abstract

Antimicrobial resistance (AMR) has emerged as a multifaceted crisis, threatening the efficacy of existing antimicrobial agents and undermining modern healthcare achievements. The evolution of resistance mechanisms, driven primarily by antimicrobial misuse and inadequate diagnostics, has accelerated the emergence of multidrug-resistant pathogens. Recent global estimates indicate that one in six bacterial infections is now resistant to commonly used antibiotics¹. This review synthesizes recent surveillance data, clinical findings, and pharmacological insights to highlight current resistance trends, underlying mechanisms, and implications for public health. Strategies for mitigation, including antimicrobial stewardship, surveillance systems, and innovation in therapeutics, are discussed, emphasizing the urgent need for coordinated global action.

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References

World Health Organization. Global antibiotic resistance surveillance report 2025: first global estimates of antimicrobial resistance. Geneva: World Health Organization; 2025.

Reza N, Shallcross L, Holmes A, et al. Antimicrobial use and resistance. BMJ. 2025;391:e082681.

Zhang R, Liu Y, Wang Z, et al. CHINET surveillance of antimicrobial resistance among clinical isolates in China, 2024. One Health Adv. 2025;3:92.

European Centre for Disease Prevention and Control. Antimicrobial resistance in the EU/EEA (EARS-Net): annual epidemiological report for 2024. Stockholm: ECDC; 2025.

Sharma R, Gupta P, Meena S, et al. Rising antimicrobial resistance patterns in tertiary care hospitals: findings from SMS Hospital, Jaipur. Times of India. 2025.

Khan MA, Ahmed S, Ali S, et al. Prevalence and clinical impact of multidrug-resistant and extensively drug-resistant respiratory pathogens in hospitalized patients. J Infect Dev Ctries. 2024;18(11):1452-1460.

World Health Organization. WHO outlines 40 research priorities on antimicrobial resistance. Geneva: World Health Organization; 2023.

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Published

2026-01-17

How to Cite

Dr. Krishna Badal. (2026). ANTIMICROBIAL RESISTANCE: PHARMACOLOGICAL AND PUBLIC HEALTH CRISIS. Journal of Applied Science and Social Science, 16(01), 337–340. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/2977

Issue

Vol. 16 No. 01 (2026): Volume 16 Issue 01

Section

Articles

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