USING CRISPR TECHNOLOGIES TO FIGHT INFECTIONS: POSSIBILITIES AND PROSPECTS.

Authors

  • Mirzakarimova Dildora Bahodirovna Associate Professor, Department of Infectious Diseases, Andijan State Medical Institute

Keywords:

CRISPR technologies, genome editing, infectious diseases, diagnostics, treatment, antibiotic resistance, pathogens, therapy.

Abstract

The article discusses the possibilities of using CRISPR technologies to fight infections, focusing on their potential for diagnosis and treatment. CRISPR, known as a revolutionary genome editing system, provides new tools to combat pathogens, including viruses and bacteria. The author analyzes various approaches to using CRISPR, such as creating highly sensitive diagnostic tests, as well as developing therapies aimed at eliminating infectious agents.

The article also discusses the prospects for using CRISPR in clinical practice, including successful examples of using the technology to treat diseases caused by antibiotic-resistant bacteria. Challenges related to safety and ethical aspects, as well as the need for further research to optimize the methods, are considered. In conclusion, it is emphasized that CRISPR has the potential not only to combat current infections but also to prepare for future epidemics, making this technology an important tool in the field of medicine and biotechnology. The article provides valuable insights for scientists, physicians, and health professionals interested in new methods of combating infectious diseases.

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References

Barrangou, R., & Doudna, J. A. (2016). Applications of CRISPR technologies in research and beyond. Nature Biotechnology, 34(9), 933-941.

Sander, J. D., & Joung, J. K. (2014). CRISPR-Cas systems for editing, regulating and targeting genomes. Nature Biotechnology, 32(4), 347-355.

Kennedy, E. M., & Cullen, B. R. (2015). Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral infections. Trends in Microbiology, 23(2), 70-73.

Cong, L., et al. (2013). Multiplex genome engineering using CRISPR/Cas systems. Science, 339(6121), 819-823.

Hsu, P. D., Lander, E. S., & Zhang, F. (2014). Development and applications of CRISPR-Cas9 for genome engineering. Cell, 157(6), 1262-1278.

Adli, M. (2018). The CRISPR tool kit for genome editing and beyond. Nature Communications, 9(1), 1911.

Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016). Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature, 533(7603), 420-424.

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Published

2024-10-26

How to Cite

Mirzakarimova Dildora Bahodirovna. (2024). USING CRISPR TECHNOLOGIES TO FIGHT INFECTIONS: POSSIBILITIES AND PROSPECTS. Journal of Applied Science and Social Science, 14(10), 135–141. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/329

Issue

Vol. 14 No. 10 (2024): Journal of Applied Science and Social Science

Section

Articles

License

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