MORPHOLOGICAL FEATURRES OF UTERINE STRACHING SYNDROME AND THE RISK OF MATERNAL MORTALITY IN MULTIPAROUS WOMEN

Authors

  • Xolboboyeva Madina Maxmarajab kizi, Axmedov Ulug’bek Xolbek ugli Termiz Institute of Economics and Service Department of Fundamental Medical Sciences Assistant

Keywords:

Multiparous uterine syndrome, pathological remodeling of the myometrium, risk of uterine rupture, hypotonic postpartum hemorrhage, pathological placental invasionm, fibroelastic proliferation, ostpartum retraction, microcirculatory disorders, obstetric risk factors, maternal mortality rates.

Abstract

This study examines the structural morphological changes occurring in the uterus of multiparous women and their direct correlation with obstetric complications, specifically the risk of maternal mortality. Repeated childbirth experiences lead to irreversible pathological remodeling of the uterine muscular tissue (myometrium).

Morphological examinations indicate a singnificant reduction in the number of  functional muscle cells (myocytes) with the uterine wall, replaced by collagen and connective tissue (fibrosis). This process drastically reduces utereni elasticity and weakens its contractile  capability (retraction). Furthermore, sclerotic changes occur in the uterine blood vessels, impairing blood circulation  

These histological alterations are the primary cause of postpartum hypotonic hemorrhage. Additionally, the thinning and scarring of the uterine wall increase the risk of uterine rupture during labor multi-fold. Research findings confirm that "multiparous uterine syndrome" is one of the most critical risk factors influencing maternal mortality rates, necessitating special attention during pregnancy and high-specialized medical care during childbirth for these patients..

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References

Obstetrics: National Guidelines / Edited by G.M. Savelyeva, G.T. Sukhikh, V.N. Serov, V.E. Radzinsky. — Moscow: GEOTAR-Media, 2018. — (Pp. 550-570: Postpartum Hemorrhage and Uterine Atony).

​2. Ailamazyan E.K. Obstetrics: Textbook for Medical Universities. — Saint Petersburg: SpetsLit, 2019. — (Pp. 320-335: Pathology of Uterine Involution).

​3. Abdullaeva L.S., Kattakhodzhaeva M.Kh. "Clinico-morphological parallels in pregnancy complicated by polyhydramnios" // Medical Journal of Uzbekistan. — 2021. — No. 2. — (Morphological consequences of uterine stretching).

​4. Russian Bulletin of Obstetrician-Gynecologist. — "Postpartum inflammatory diseases of the uterus". — 2022. — No. 4. — (Analysis of postpartum complications).

​5. Postpartum Period: Clinic, Management (Educational manual). — Tashkent, 2020

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Published

2026-02-14

How to Cite

Xolboboyeva Madina Maxmarajab kizi, Axmedov Ulug’bek Xolbek ugli. (2026). MORPHOLOGICAL FEATURRES OF UTERINE STRACHING SYNDROME AND THE RISK OF MATERNAL MORTALITY IN MULTIPAROUS WOMEN. Journal of Applied Science and Social Science, 16(02), 631–634. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/3295

Issue

Vol. 16 No. 02 (2026): Volume 16 Issue 02

Section

Articles

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