HOW STRESS AFFECTS HUMAN HEALTH

Authors

  • Karlibaeva Ulbosin Jangabay kizi,Orazbaev Nuraliy Amanaliyevich,Nortojiyev Muhammad Anvar ugli 215-“A” group ,The Second Faculty of General Medicine 116-“B”group ,Tashkent State Medical University Teacher

Keywords:

Stress, acute stress, chronic stress, hypostress, eustress, Yerkes–Dodson law, cortisol, adrenaline, oxytocin, endorphins, serotonin, HPA axis, psychological balance, toxic stress, burnout, cognitive development, adaptation.

Abstract

This article comprehensively analyzes the phenomenon of stress, which is one of the most pressing problems of modern psychology and physiology. In the research, along with the traditional classification of stress — acute, episodic, and chronic types — the negative consequences of hypostress (lack of stress), a condition that has been little studied but is dangerous for human life, are thoroughly explained. Based on the Yerkes–Dodson law, the importance of the “golden mean” necessary for human efficiency and the concept of beneficial stress (eustress) are revealed. In the central part of the article, the biochemical mechanisms of stress are analyzed, in particular the activity of the hypothalamus–pituitary–adrenal axis (HPA axis) and the effects of the hormones cortisol and adrenaline on the organism. Additionally, age-related characteristics of stress — toxic stress in childhood, emotional instability in adolescence, and occupational “burnout” in adults — are compared, and strategies for activating natural antidotes such as oxytocin, endorphin, and serotonin hormones are recommended.

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References

Selye, H. (1950). The Physiology and Pathology of Exposure to Stress. Montreal: Acta Inc.

Yerkes, R. M., & Dodson, J. D. (1908). The relation of strength of stimulus to rapidity of habit-formation. Journal of Comparative Neurology and Psychology, 18(5), 459–482.

McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Reviews, 87(3), 873–904.

Sapolsy, R. M. (2004). Why Zebras Don't Get Ulcers: The Acclaimed Guide to Stress, Stress-Related Diseases, and Coping. Holt Paperbacks.

Shonkoff, J. P., & Garner, A. S. (2012). The lifelong effects of early childhood adversity and toxic stress. Pediatrics, 129(1), e232–e246.

American Psychological Association (2021). Stress in America: A National Health Crisis.

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Published

2026-04-18

How to Cite

Karlibaeva Ulbosin Jangabay kizi,Orazbaev Nuraliy Amanaliyevich,Nortojiyev Muhammad Anvar ugli. (2026). HOW STRESS AFFECTS HUMAN HEALTH. Journal of Applied Science and Social Science, 16(4), 824–826. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/4102