INFLUENCE OF FEEDING RATS WITH STARCH COMBINED WITH CASEIN AND CASEIN HYDROLYSATES ON CHANGES IN THE ABSORPTION OF GLUCOSE AND AMINO ACIDS INTO THE BLOOD

Authors

  • Kasimova Diyora Sobirjonovna,Vladimir Alekseevich Aleynik,Babich Svetlana Mihaelovna,Khamrakulov Sharifjon Khashimovich assitant ,DSc, professor ,DSc, docent,DSc,docent Andijan State Medical Institute , Andijan, ,Uzbekistan

Keywords:

starch, casein, interaction, digestion, absorption, feeding, rats, glucose, amino acids.

Abstract

The work studied in vitro the effect of feeding rats with starch together with casein and casein hydrolysates on changes in the absorption of glucose and amino acids into the blood. The study found that feeding rats with starch together with casein contributes to lower blood glucose levels compared to similar results of feeding rats only with starch and amino acids only with casein. At the same time, feeding rats with starch together with casein hydrolysate promotes a more pronounced decrease in glucose, which was less than the indicators of feeding only starch, and starch together with casein. Also, a pronounced decrease in amino acids, less than the indicators of feeding only casein, and starch together with casein. These changes may be associated with the formation of starch-casein, as well as starch-peptide complexes that prevent the hydrolysis of starch by salivary amylase and casein and casein hydrolysates by gastric juice.

Downloads

Download data is not yet available.

References

Симонян А. В. Саламатов, А. А., Покровская, Ю. С., & Аванесян, А. А. Использование нингидриновой реакции для количественного определения α-аминокислот в различных объектах: методические рекомендации //Метод. рек., Волгоград, Изд-во ВолГМУ. – 2007. –106. С.

Augustin, L. S., Kendall, C. W., Jenkins, D. J., Willett, W. C., Astrup, A., Barclay, A. W., ... & Poli, A. Glycemic index, glycemic load and glycemic response: an International Scientific Consensus Summit from the International Carbohydrate Quality Consortium (ICQC) //Nutrition, Metabolism and cardiovascular diseases. – 2015. – Т. 25. – №. 9. – С. 795-815.

Brand-Miller J. C. Brand-Miller, J. C., Stockmann, K., Atkinson, F., Petocz, P., & Denyer, G. Glycemic index, postprandial glycemia, and the shape of the curve in healthy subjects: analysis of a database of more than 1000 foods //The American journal of clinical nutrition. – 2009. – Т. 89. – №. 1. – С. 97-105.

Derakhshan, A., Tohidi, M., Arshi, B., Khalili, D., Azizi, F., & Hadaegh, F. Relationship of hyperinsulinaemia, insulin resistance and β‐cell dysfunction with incident diabetes and pre‐diabetes: the Tehran Lipid and Glucose Study //Diabetic Medicine. – 2015. – Т. 32. – №. 1. – С. 24-32.

Kett A. P. et al. Influence of milk proteins on the pasting behaviour and microstructural characteristics of waxy maize starch //Food Hydrocolloids. – 2013. – Т. 30. – №. 2. – С. 661-671

Lennerz, B. S., Koutnik, A. P., Azova, S., Wolfsdorf, J. I., & Ludwig, D. S. Carbohydrate restriction for diabetes: rediscovering centuries-old wisdom //Journal of Clinical Investigation. – 2021. – Т. 131. – №. 1. – С. 1-12.

Meng H. et al. Effect of macronutrients and fiber on postprandial glycemic responses and meal glycemic index and glycemic load value determinations //The American journal of clinical nutrition. – 2017. – Т. 105. – №. 4. – С. 842-853.

Saltiel A. R. Insulin signaling in health and disease //The Journal of Clinical Investigation. – 2021. – Т. 131. – №. 1. – С. 142241-142241.

Tay, J., Luscombe-Marsh, N. D., Thompson, C. H., Noakes, M., Buckley, J. D., Wittert, G. A., ... & Brinkworth, G. D. A very low-carbohydrate, low–saturated fat diet for type 2 diabetes management: a randomized trial //Diabetes care. – 2014. – Т. 37. – №. 11. – С. 2909-2918.

Zafar, M. I., Mills, K. E., Zheng, J., Regmi, A., Hu, S. Q., Gou, L., & Chen, L. L. Low-glycemic index diets as an intervention for diabetes: a systematic review and meta-analysis //The American journal of clinical nutrition. – 2019. – Т. 110. – №. 4. – С. 891-902.

Downloads

Published

2025-01-16

How to Cite

Kasimova Diyora Sobirjonovna,Vladimir Alekseevich Aleynik,Babich Svetlana Mihaelovna,Khamrakulov Sharifjon Khashimovich. (2025). INFLUENCE OF FEEDING RATS WITH STARCH COMBINED WITH CASEIN AND CASEIN HYDROLYSATES ON CHANGES IN THE ABSORPTION OF GLUCOSE AND AMINO ACIDS INTO THE BLOOD. Journal of Applied Science and Social Science, 15(01), 80–87. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/514