MORPHOLOGICAL AND PATHOLOGICAL CHANGES IN THE LUNGS DUE TO COVID-19

Authors

  • Xolieva Nigora Khudayberdievna , Mahkamova Mohbegim Aziz kizi Abdullayev ,Baxtiyor Abdumannop o'g'li ,Rakhmatullayeva Sabrina Kamolovna Scientific Advisor,Students of Tashkent Medical Academy

Keywords:

COVID-19, SARS-CoV-2, lung pathology, alveolar damage, fibrosis, thrombosis, cytokine storm, microthrombosis, diffuse alveolar damage (DAD), pulmonary fibrosis.

Abstract

The COVID-19 pandemic has significantly impacted not only global healthcare systems but also the human body. The SARS-CoV-2 virus damages both the upper and lower respiratory tracts, leading to severe inflammatory processes in the lungs. The acute and chronic phases of this disease can cause serious pathological conditions such as alveolar damage, microthrombosis, and fibrosis.

This article provides a comprehensive review of the morphological and pathological changes in the lungs due to COVID-19, explaining how the virus affects alveolar cells, triggers inflammatory processes, and leads to long-term complications.

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References

Zhu, N., Zhang, D., Wang, W., et al. (2020). A novel coronavirus from patients with pneumonia in China, 2019. The New England Journal of Medicine, 382(8), 727-733.

Carsana, L., Sonzogni, A., Nasr, A., et al. (2020). Pulmonary post-mortem findings in a large series of COVID-19 cases from Northern Italy. The Lancet Infectious Diseases, 20(10), 1135-1140.

Ackermann, M., Verleden, S. E., Kuehnel, M., et al. (2020). Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in COVID-19. The New England Journal of Medicine, 383(2), 120-128.

Xu, Z., Shi, L., Wang, Y., et al. (2020). Pathological findings of COVID-19 associated with acute respiratory distress syndrome. The Lancet Respiratory Medicine, 8(4), 420-422.

Varga, Z., Flammer, A. J., Steiger, P., et al. (2020). Endothelial cell infection and endotheliitis in COVID-19. The Lancet, 395(10234), 1417-1418.

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Published

2025-02-11

How to Cite

Xolieva Nigora Khudayberdievna , Mahkamova Mohbegim Aziz kizi Abdullayev ,Baxtiyor Abdumannop o'g'li ,Rakhmatullayeva Sabrina Kamolovna. (2025). MORPHOLOGICAL AND PATHOLOGICAL CHANGES IN THE LUNGS DUE TO COVID-19. Journal of Applied Science and Social Science, 15(02), 151–155. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/577

Issue

Vol. 15 No. 02 (2025): Journal of Applied Science and Social Science

Section

Articles

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