CHRONIC PAIN

Authors

  • Asatullayev Rustamjon Baxtiyarovich,Ergashov Zafar Baxtiyorovich Scientific supervisor,Student

Keywords:

Chronic tonsillitis, bacterial biofilms, immune dysregulation, recurrent infections, tonsillectomy, peritonsillar abscess, obstructive sleep apnea, microbiological testing, antibiotic therapy, personalized medicine

Abstract

Chronic tonsillitis is a persistent inflammation of the palatine tonsils, often resulting from recurrent bacterial or viral infections. The condition is characterized by symptoms such as persistent sore throat, bad breath, and difficulty swallowing, which can significantly impact a patient’s quality of life. The underlying pathophysiology involves bacterial biofilms, immune dysregulation, and chronic inflammation leading to hypertrophy and cryptic debris accumulation. Diagnosis relies on clinical assessment, microbiological testing, and imaging studies when complications are suspected. Management strategies range from conservative treatments, including antibiotics and anti-inflammatory medications, to surgical intervention via tonsillectomy in severe or recurrent cases. Complications of untreated chronic tonsillitis can include peritonsillar abscesses, systemic infections, and obstructive sleep apnea. Ongoing research into biofilm resistance and immune modulation may lead to more effective therapeutic approaches in the future.

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References

Brook, I. (2005). The role of bacterial biofilms in chronic tonsillitis. Otolaryngology-Head and Neck Surgery, 132(5), 526-530.

Burton, M. J., & Glasziou, P. P. (2009). Tonsillectomy or adenotonsillectomy versus non-surgical treatment for chronic/recurrent acute tonsillitis. Cochrane Database of Systematic Reviews, 1, CD001802.

Windfuhr, J. P., & Werner, J. A. (2013). Tonsillitis and its complications: A clinical review. The Journal of Laryngology & Otology, 127(4), 386-392.

Powell, J., & Wilson, J. A. (2012). An evidence-based approach to recurrent tonsillitis in adults.Clinical Otolaryngology, 37(5), 407-409.

Schwaab, M., Derkay, C., Reilly, J., Kenna, M., Skenazy, S., & Ossoff, R. H. (1999). Microbiology of recurrent tonsillitis. Archives of Otolaryngology-Head & Neck Surgery, 125(12), 1325-1329.

Moser, K., et al. (2021). Epstein-Barr virus infection and its role in chronic tonsillitis. Journal of Clinical Virology, 135, 104703.

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Published

2025-02-22

How to Cite

Asatullayev Rustamjon Baxtiyarovich,Ergashov Zafar Baxtiyorovich. (2025). CHRONIC PAIN. Journal of Applied Science and Social Science, 15(02), 472–474. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/650