COMPARATIVE ANALYSIS OF BREAST CANCER RELAPSE TIME: STATISTICAL MODELING ACROSS DIFFERENT TREATMENTS

Authors

  • Olivia Williams Department of Mathematics and Statistics, Victoria University of Wellington, Wellington, Newzeland

Keywords:

Breast Cancer, Relapse Time, Treatment Comparison

Abstract

Breast cancer remains a significant global health concern, and understanding the factors influencing relapse time is crucial for treatment planning and patient management. This study presents a comparative analysis of breast cancer relapse time across different treatments using statistical modeling techniques. Data from patients who underwent various treatment regimens were analyzed to identify factors associated with relapse time. Cox proportional hazards models were employed to assess the impact of treatment type, patient demographics, tumor characteristics, and other clinical variables on relapse time. The findings provide valuable insights into the effectiveness of different treatment modalities and their influence on breast cancer recurrence.

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References

Akaike, H., 1974. A new look at the statistical model identification. IEEE Trans. Autom. Control, 19: 716-723.

Boag, J.W., 1949. Maximum likelihood estimates of the proportion of patients cured by cancer therapy. J. R. Stat. Soc., 11: 15-44.

Fabien, C. and J. Pierre, 2007. A SAS macro for parametric and semiparametric mixture models. Comput. Meth. Programs Biomed., 85: 173-180.

Eleni, A. and N.H. Gabriel, 2008. Prognostic factors in metastatic breast cancer successes and challenges toward individualized therapy. J. Clin. Oncol., 26: 3360-3662.

Freedman, R.A., Y. He, E.P. Winer and N.L. Keating, 2009. Trends in racial and age disparities in definitive local therapy of early-stage breast cancer. J. Clin. Oncol., 27: 713-719.

Fyles, A.W., D.R. McCready, L.A. Manchul , M.E. Trudeau and P. Merante, 2004. Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer. NEJM., 351: 963-970.

Ghitany, M.E., R.A. Maller and S. Zhou, 1992. Exponential mixture models with long-term survivors and covariates. Technical Report, The University of Western Australia.

Farewell, V.T., 1982. The use of mixture models for the analysis of survival data with long-term survivors. Biometrics, 38: 1041-1046.

Goldman, A.I., 1984. Survivorship analysis when cure is a possibility: A monte carlo study. Stat. Med., 3: 153-163.

Habibi, G., S. Leung, J.H. Law, K. Gelmon and H. Masoudi et al., 2008. Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtyples. BCR., 10: 86-86.

Hershman, D.L., D. Buono, R.B. McBride, W.Y. Tsai, K.A. Joseph, V.R. Grann and J.S. Jacobson, 2008. Surgeon characteristics and receipt of adjuvant radiotherapy in women with breast cancer. J. Nat. Cancer Inst., 100: 199-206.

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Published

2014-07-03

How to Cite

Olivia Williams. (2014). COMPARATIVE ANALYSIS OF BREAST CANCER RELAPSE TIME: STATISTICAL MODELING ACROSS DIFFERENT TREATMENTS. Journal of Applied Science and Social Science, 4(02), 01–07. Retrieved from https://www.internationaljournal.co.in/index.php/jasass/article/view/95