OPTIMIZING CHROMATOGRAPHIC SEPARATION: ANALYTICAL METHOD DEVELOPMENT FOR NINE HALOACETIC ACIDS IN WATER SAMPLES
Keywords:
Haloacetic acids, water samples, chromatographic separationAbstract
The detection and quantification of haloacetic acids (HAAs) in water samples are of paramount importance due to their potential health risks. In this study, an analytical method was developed for the separation of nine haloacetic acids commonly found in water sources. The method involved optimizing chromatographic conditions using high-performance liquid chromatography (HPLC) coupled with ultraviolet (UV) detection. Parameters such as mobile phase composition, column type, and detection wavelength were systematically varied to achieve optimal separation and sensitivity. The developed method demonstrated excellent separation efficiency, resolution, and sensitivity for all nine HAAs, enabling accurate quantification in water samples. This method holds great promise for routine monitoring of HAAs in water treatment facilities and environmental monitoring programs.
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Copyright (c) 2015 G. Ayutthaya
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