Understanding the determinants of portfolio flows is crucial for policymakers and investors alike, especially in emerging markets like Ghana. This study provides a comprehensive analysis of the factors influencing portfolio flows to Ghana, drawing on empirical data and econometric techniques. By examining a wide range of variables such as economic indicators, financial market conditions, and external factors, we identify key drivers of portfolio investment in Ghana. Our findings contribute to a deeper understanding of the dynamics shaping capital flows to the country and offer valuable insights for policymakers seeking to attract and retain foreign investment.